Comprehensive Guide to the Axillary Artery: Structure, Function, and Clinical Significance

The axillary artery is a vital component of the upper limb’s vascular system, playing a crucial role in supplying blood to the arm, shoulder, and chest wall. As a continuation of the subclavian artery, the axillary artery is central to maintaining circulation in the upper extremities and supports numerous clinical and surgical applications. This SEO-optimized article explores the anatomy, anatomical landmarks, blood supply, clinical relevance, and common pathologies related to the axillary artery—essential knowledge for medical professionals, students, and health enthusiasts.


Understanding the Context

What is the Axillary Artery?

The axillary artery (also known as the arteria axillaris) is a major blood vessel located in the upper limb, arising from the subclavian artery just beneath the lateral border of the first rib. It runs anterior to the posterior edge of the pectoralis minor muscle and progresses downward into the axilla (armpit), where it transitions into the brachial artery.

As the major terminal branch of the subclavian artery, the axillary artery supplies oxygenated blood to the arm, deltoid muscle, pectoral region, and parts of the thoracic wall. Its position and function make it a critical focus in vascular anatomy, surgery, and trauma care.


Key Insights

Anatomical Structure and Branches

The axillary artery is typically divided into four segments based on its relationship to the pectoralis minor muscle:

  1. First segment
    – Located between the clavicle and pectoralis minor
    – Gives off the thoracoacromial artery and geniculate artery

  2. Second segment
    – Passes under the pectoralis minor
    – Supplies structure through the infraclavicular (mammarial) region
    – Supplies the shoulder and thoracic wall via branches like the deep circumflex humeral artery and second thoracoacromial artery

  3. Third segment
    – Located posterior to the pectoralis minor
    – Distinguished by the presence of the third thoracoacromial artery

Final Thoughts

  1. Fourth segment
    – Extends from the muscle to the axillary fossa (armpit)
    – Continues as the brachial artery, supplying the forearm and hand

Alongside these branches, the axillary artery also gives rise to the deep branch of the axillary nerve, contributing to innervation of certain shoulder muscles.


Blood Supply and Functional Role

The axillary artery is the principal transporter of oxygen-rich arterial blood to the upper limb. Its branches ensure perfusion to:

  • Deltoid and pectoral muscles
  • Skin and tendons of the shoulder and arm
  • Axillary lymph nodes and surrounding tissues
  • Structural support to the clavicular and thoracic regions

Due to its length and branching pattern, the axillary artery can be palpated clinically in the axilla, especially during physical examinations involving pulse assessment or vascular interventions.


Clinical Significance

1. Clinical Palpation and Diagnosis